Archived: Vaccine Information and Safety Studies | Vaccine Safety | CDC

This is a simplified archive of the page at

Use this page embed on your own site:

Get the latest vaccine safety guidance from CDC, including safety information for recommended vaccines, safety studies, and consultation for health professionals.

vaccine, safety of vaccines, safety study, immunization safety, immunization safety office, cisa, vaers, vsd, Vaccine SafetyReadArchived

Get Started with v-safe

Get Started with v-safe, together

Use your smartphone to tell CDC about any side effects after getting the COVID-19 vaccine. You’ll also get reminders if you need a second vaccine dose.

The United States currently has the safest vaccine supply in its history. The nation’s long-standing vaccine safety system ensures that vaccines are as safe as possible.

Vaccine Safety is a vital part of the nation’s response to the COVID-19 pandemic. As vaccines are developed and become available, the public’s knowledge of their safety, both initially and during extended use, is an important part of a successful national vaccination effort.

CDC’s Immunization Safety Office works to communicate timely and transparent information about the safety of vaccines to public health officials, healthcare providers, and the public. The office conducts vaccine safety monitoring and clinical research to help keep vaccines safe.

Report a Possible Health Problem following
Vaccination to VAERS

Everyone is encouraged to report possible health problems (adverse events) after vaccination to the Vaccine Adverse Event Reporting System (VAERS). Healthcare providers and vaccine manufacturers are required to report certain health events.

Learn Moreexternal icon

Healthcare providers or health departments in the United States can request a consultation for complex COVID-19 vaccine safety questions from CISA COVIDvax.

Learn More

Vaccine and syringe injection It use for prevention, immunization and treatment from COVID-19

Vaccine Safety is a top priority while CDC and federal partners work to make COVID-19 vaccines available.

screenshot top of VAERS hompage

The Vaccine Adverse Event Reporting System (VAERS) serves as the nation’s early warning system to monitor for potential vaccine safety problems. Anyone can report possible health problems to VAERS.

VSD map

The Vaccine Safety Datalink (VSD) is a collaboration between CDC and 9 health care organizations that conducts active vaccine safety monitoring and research.

CISA Project Map

The Clinical Immunization Safety Assessment (CISA) Project is a partnership between CDC and 7 medical research centers that provides expert consultation and conducts clinical research on vaccine-associated health risks.